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Transitioning to a Pea Protein Plant-Based Enteral Formula (PPPBF) Supports Gastrointestinal and Metabolic Health in Tube-Fed Medically Complex Adults

Authors: N. Withrow1, J. Franck2, C. Anderson2

Research Presented as a Poster at the 2025 Annual Congress for The European Society for Clinical Nutrition and Metabolism (ESPEN)

Population and Design

  • Retrospective medical chart review of 20 adults (21-58 years) with complex medical conditions—in a residential care home—that had their tube feeding formulas switched from conventional to organic pea protein-based formulas for 3 months.

  • Primary medical diagnosis was cerebral palsy in 75% of study participants.

Outcomes Measured

  • Frequency and types of bowel movements (Bristol Stool Scale), weight changes, medication use, and laboratory results.

Results

  • After switching to organic pea protein-based formulas, participants’ mean daily fiber intake increased from 4.7 g to 16.1 g.

  • Study participants experienced significantly fewer severe diarrheal episodes (p=0.025).

  • Seventy percent (70%) of participants also experienced a significant decrease in Hemoglobin A1c levels (p=0.001).

  • Weight, medication usage, and other laboratory values remained stable throughout the study.

Affiliations:

1. Kate Farms, Goleta, CA, United States

2. Nutrition, The Center for Discovery, Harris, NY, United States

Citation:

Withrow N et al, Clin Nutr ESPEN, vol 69, p1154-1155, October 2025