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Patient-Reported Outcomes on Gastrointestinal Tolerance and Adherence to a Pea Protein Plant-Based Enteral Formula in Children and Adults

Authors: Stanley A. Cohen1, Vanessa Millovich2, Dwan Newman2, Nicole Withrow2, Lucille Beseler3 and Christina J. Valentine2

Manuscript Published in Frontiers in Nutrition

Population and Design

  • Survey of 392 children and adults that purchased organic pea protein-based formulas via the manufacturer’s online website. Formula users or their caregivers reported health outcomes on a 5-point scale of agreement.

Outcomes Measured

  • Demographic characteristics, reported general health, formula use characteristics, and outcomes on gastrointestinal symptoms referred to as intolerance and adherence

Results

  • Common primary diagnoses were gastroparesis (16.8%), cancer (8.7%), failure to thrive (7.9%), or malnutrition (7.4%).

  • Respondents either consumed the organic pea protein-based formulas orally (n = 210) or via a feeding tube (n = 182). About one-half were on these formulas for greater than 6 months.

  • Up to 67% of survey respondents reported improved GI symptoms.

  • Weight gain was reported in 58.3% of formula users, 27.7% reported no change in weight, and 6.4% reported weight loss.

  • Furthermore, 83% of survey respondents adhered to the organic pea protein-based formulas.

Affiliations:

1. Children’s Center for Digestive Health Care, Morehouse School of Medicine, Atlanta, GA, United States

2. Kate Farms, Goleta, CA, United States

3. Family Nutrition Center of South Florida, Boca Raton, FL, United States

Citation:

Cohen SA et al., 2025; Front Nutr, 12: 1619884